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The regulatory sciences for stem cell-based medicinal products

Bao-Zhu Yuan,Junzhi Wang

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 190-200 doi: 10.1007/s11684-014-0323-5

Abstract: Moreover, some stem cell-based products have been approved for marketing by different national regulatoryexist and need to be urgently addressed, especially in countries where establishment of appropriate regulatoryMore relevantly, the stem cell regulatory sciences need to be established or improved to more effectivelyevaluate quality, safety and efficacy of stem cell products, and for building up the appropriate regulatoryregulations, and the associated challenges, and we then propose some considerations for improving stem cell regulatory

Keywords: cell-based medicinal products (SCMPs)     stem cell therapy (SCT)     safety     effectiveness     standards     guidelines     regulatory    

Technology and system of constraint programming for industry production scheduling

Yarong CHEN, Zailin GUAN, Yunfang PENG, Xinyu SHAO, Muhammad HASSEB

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 4,   Pages 455-464 doi: 10.1007/s11465-010-0106-x

Abstract: The use of techniques and system of constraint programming enables the implementation of precise, flexibleThis paper systematically introduces the constraint modeling and solving technology for production schedulingWe trend of some concrete technology, such as modeling, search, constraint propagation, consistency,and optimization of constraint programming for scheduling problems.application analysis, a generic application framework for real-life scheduling based on commercial constraint

Keywords: constraint programming     production scheduling     constraint propagation     search     consistency     optimization    

Zero E-waste: Regulatory impediments and blockchain imperatives

Mengjun Chen, Oladele A. Ogunseitan

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1402-x

Abstract: Increasingly, 3re implementation is restricted by regulatory difficulties, particularly the invocation

Keywords: Blockchain     E-waste     Regulatory Policy     Copyright Laws     Repair-Reuse-Remanufacture     Toxicity    

Disinfection byproducts in drinking water and regulatory compliance: A critical review

Xiaomao WANG,Yuqin MAO,Shun TANG,Hongwei YANG,Yuefeng F. XIE

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 1,   Pages 3-15 doi: 10.1007/s11783-014-0734-1

Abstract: This critical review focuses on the issues associated with DBP regulatory compliance, including methodsPrecursor removal and alternative disinfectants are common practices for DBP regulatory compliance.

Keywords: Disinfection byproducts (DBPs)     drinking water standards     regulatory compliance     alternative disinfection    

Liver cell therapies: cellular sources and grafting strategies

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 432-457 doi: 10.1007/s11684-023-1002-1

Abstract: development of genetic sequencing technologies, research on the liver’s cellular composition and its regulatory

Keywords: liver regeneration     hepatocytes     cholangiocytes     stem cells     organoids     regulatory mechanisms     transplantation    

Low-Cost Federated Broad Learning for Privacy-Preserved Knowledge Sharing in the RIS-Aided Internet of

Xiaoming Yuan,Jiahui Chen,Ning Zhang,Qiang Ye,Changle Li,Chunsheng Zhu,Xuemin Sherman Shen,

Engineering doi: 10.1016/j.eng.2023.04.015

Abstract: participating clients, we construct a joint resource allocation and reconfigurable intelligent surface (RISdouble Davidon–Fletcher–Powell (DDFP) algorithm is presented to solve the time slot allocation and RIS

Keywords: Knowledge sharing     Internet of Vehicles     Federated learning     Broad learning     Reconfigurable intelligent surfaces     Resource allocation    

Recent development in low-constraint fracture toughness testing for structural integrity assessment of

Jidong KANG, James A. GIANETTO, William R. TYSON

Frontiers of Mechanical Engineering 2018, Volume 13, Issue 4,   Pages 546-553 doi: 10.1007/s11465-018-0501-2

Abstract: Such a test provides high constraint and therefore conservative fracture toughness results.However, for girth welds in service, defects are usually subjected to primarily tensile loading where the constraintLow-constraint toughness tests represent more realistic loading conditions for girth weld defects, andIn this review, we present recent developments in low-constraint fracture toughness testing, specifically

Keywords: fracture toughness     constraint effect     single-edge-notched tension test     pipeline     structural integrity assessment    

Development of rocking constraint device with vertical damping capacity for three-dimensional base-isolated

Frontiers of Structural and Civil Engineering 2023, Volume 17, Issue 3,   Pages 350-367 doi: 10.1007/s11709-022-0923-0

Abstract: A new rocking constraint device (RCD) is developed for three-dimensional (3D) base-isolated frame structuresinstalled outside the cylinders when the superstructure undergoes translational motion, and rocking constraintTheoretical formulas for calculating the damping and rocking constraint stiffness of the RCD are proposedtests are conducted at different loading frequencies and amplitudes to verify the damping and rocking constraintloading frequency, the average vertical stiffness of the two cylinders, which determines the rocking constraint

Keywords: three-dimensional isolation     rocking behavior     rocking constraint device     replaceable damping component    

Research on constraint-based virtual assembly technologies

YANG Rundang, WU Dianliang, FAN Xiumin, YAN Juanqi

Frontiers of Mechanical Engineering 2007, Volume 2, Issue 2,   Pages 243-249 doi: 10.1007/s11465-007-0043-5

Abstract: To realize a constraint-based virtual assembly operation, the unified representations of the assemblyconstraint, the equivalent relation between the constraint and the degree of freedom (DOF), and theSeveral algorithms about the constraint treatment are submitted.Second, to satisfy the new constraint, according to the positing solving algorithm, the position andExperiments have indicated that these algorithms have well supported constraint treatments in the IVAE

Keywords: movement DOF     recognition algorithm     assembly     orientation     combination    

Topology optimization of transient problem with maximum dynamic response constraint using SOAR scheme

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 3,   Pages 593-606 doi: 10.1007/s11465-021-0636-4

Abstract: for the continuum topology optimization of transient vibration problem with maximum dynamic response constraintaggregated index in the form of an integral function is presented to cope with the maximum response constraint

Keywords: topology optimization     solid isotropic material with penalization     transient response     aggregation function     second-order Arnoldi reduction    

METABOLIC AND TRANSCRIPTOME ANALYSIS REVEALS METABOLITE VARIATION AND FLAVONOID REGULATORY NETWORKS IN

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract: Here, we focus on the seasonal variation in metabolites of fresh tea shoots and their regulatory mechanismThe regulatory pathway was explored by constructing a metabolite correlation network and a weighted gene

Fast removal of ocular artifacts from electroencephalogram signals using spatial constraint independent

Bang-hua YANG,Liang-fei HE,Lin LIN,Qian WANG

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 6,   Pages 486-496 doi: 10.1631/FITEE.1400299

Abstract: To remove ocular artifacts from EEG in brain-computer interfaces (BCIs), a method named spatial constraintIn the second stage, first, SCICA applies exact artifact ICs obtained in the first stage as a constraintThese extracted ICs are called spatial constraint ICs (SC-ICs).

Keywords: artifacts     Electroencephalogram (EEG)     Electrooculogram (EOG)     Brain-computer interface (BCI)     Spatial constraint    

A Study About IC and IR in Principal-gent RelationshipUnder the Engineer Supervision Institution

Qin Xuan

Strategic Study of CAE 2007, Volume 9, Issue 4,   Pages 45-49

Abstract:

According to principal-agent theory, the Incentive compatibility constraint(IC)and the participation constraint (IR) in principal-gent relationship between employer and engineerThe conclusions are drawn:The incentive compatibility constraint (IC) is more important than participationconstraint (IR), If the mechanism doesn't satisfy the needs of IC, then it will be inefficient.

Keywords: engineer supervision     employer     engineer     principal-gent     incentive compatibility constraint(IC)     participationconstraint(IR)    

Research on the influence of contact surface constraint on mechanical properties of rock-concrete composite

Baoyun ZHAO, Yang LIU, Dongyan LIU, Wei HUANG, Xiaoping WANG, Guibao YU, Shu LIU

Frontiers of Structural and Civil Engineering 2020, Volume 14, Issue 2,   Pages 322-330 doi: 10.1007/s11709-019-0594-7

Abstract: The influence of contact surface constraint on the mechanical properties of rock-concrete composite specimensResults show that the stress and strain of rock-concrete composite specimens with contact surface constraintAveragely, compared with composite specimens without the contact surface, the existence of contact surface constraintof the fracture surface, the theory of microcrack development is used to explain the contact surface constraint

Keywords: rock-concrete     composite specimen     contact surface     mechanical properties     failure mechanism    

Regulatory T Cells and Their Clinical Applications in Antitumor Immunotherapy Review

Feng Xie, Rui Liang, Dan Li, Bin Li

Engineering 2019, Volume 5, Issue 1,   Pages 132-139 doi: 10.1016/j.eng.2018.12.002

Abstract: Regulatory T cells (Tregs) are a subgroup of suppressive CD4+ T cells that play a vital role in the maintenance

Keywords: Regulatory T cells     Cancer     Immunotherapy    

Title Author Date Type Operation

The regulatory sciences for stem cell-based medicinal products

Bao-Zhu Yuan,Junzhi Wang

Journal Article

Technology and system of constraint programming for industry production scheduling

Yarong CHEN, Zailin GUAN, Yunfang PENG, Xinyu SHAO, Muhammad HASSEB

Journal Article

Zero E-waste: Regulatory impediments and blockchain imperatives

Mengjun Chen, Oladele A. Ogunseitan

Journal Article

Disinfection byproducts in drinking water and regulatory compliance: A critical review

Xiaomao WANG,Yuqin MAO,Shun TANG,Hongwei YANG,Yuefeng F. XIE

Journal Article

Liver cell therapies: cellular sources and grafting strategies

Journal Article

Low-Cost Federated Broad Learning for Privacy-Preserved Knowledge Sharing in the RIS-Aided Internet of

Xiaoming Yuan,Jiahui Chen,Ning Zhang,Qiang Ye,Changle Li,Chunsheng Zhu,Xuemin Sherman Shen,

Journal Article

Recent development in low-constraint fracture toughness testing for structural integrity assessment of

Jidong KANG, James A. GIANETTO, William R. TYSON

Journal Article

Development of rocking constraint device with vertical damping capacity for three-dimensional base-isolated

Journal Article

Research on constraint-based virtual assembly technologies

YANG Rundang, WU Dianliang, FAN Xiumin, YAN Juanqi

Journal Article

Topology optimization of transient problem with maximum dynamic response constraint using SOAR scheme

Journal Article

METABOLIC AND TRANSCRIPTOME ANALYSIS REVEALS METABOLITE VARIATION AND FLAVONOID REGULATORY NETWORKS IN

Journal Article

Fast removal of ocular artifacts from electroencephalogram signals using spatial constraint independent

Bang-hua YANG,Liang-fei HE,Lin LIN,Qian WANG

Journal Article

A Study About IC and IR in Principal-gent RelationshipUnder the Engineer Supervision Institution

Qin Xuan

Journal Article

Research on the influence of contact surface constraint on mechanical properties of rock-concrete composite

Baoyun ZHAO, Yang LIU, Dongyan LIU, Wei HUANG, Xiaoping WANG, Guibao YU, Shu LIU

Journal Article

Regulatory T Cells and Their Clinical Applications in Antitumor Immunotherapy

Feng Xie, Rui Liang, Dan Li, Bin Li

Journal Article